Vibramycin is the brand name for the generic antibiotic doxycycline. It belongs to a class of antibiotics called tetracyclines and is a commonly prescribed medication used to treat a variety of bacterial infections. In this article, we will take a deeper look at what Vibramycin is, what infections it treats, how it works, dosage and usage guidelines, side effects, and the price of Vibramycin in Pakistan.
What is Vibramycin?
Vibramycin contains doxycycline hyclate as the active ingredient. It stops the growth and spread of bacteria in the body. Doxycycline is a broad-spectrum antibiotic, meaning it works against a wide range of bacteria. Vibramycin was first introduced in 1967 and is manufactured by Pfizer’s pharmaceutical company. It is available in multiple formulations including tablets, capsules, syrup, and intravenous injections. The regular tablets come in different strengths like 50mg, 100mg, and 200mg.
Vibramycin Tablet Uses
Doxycycline is indicated for the treatment of many common bacterial infections. These include respiratory tract infections like pneumonia, bronchitis, sinus infections, and tonsillitis. It is also used for skin infections like acne, urinary tract infections, sexually transmitted diseases like chlamydia, and eye infections like conjunctivitis. In addition, it can be used to treat typhus, cholera, leptospirosis, and certain sexually transmitted diseases. It is also an alternative drug for malaria prevention and treatment.
How does Vibramycin work?
Doxycycline works by preventing bacteria from producing proteins that are essential for their growth and replication. It binds to the 30S ribosomal subunit of the bacterial cells and blocks the binding of aminoacyl tRNA to the mRNA-ribosome complex. This prevents the addition of amino acids to the growing peptide chain, which eventually leads to inhibition of protein synthesis. Without the ability to synthesize proteins, the bacteria cannot carry out vital cellular functions, so they fail to multiply and ultimately die off.
Dosage and Administration
The standard dosage of Vibramycin for adults is 100mg to 200mg per day taken as a single dose or divided in two doses. It may be taken with or without food but preferably with a full glass of water. For severe infections, the dose can be increased to a maximum of 600 mg per day. For children above 8 years old, the usual dose is 2 mg per kg body weight.
Vibramycin should be taken at the same times each day to maintain adequate levels of the drug in the bloodstream. The typical treatment period is 7 to 14 days but it depends on the type and severity of infection. It is important to complete the full course even after symptoms improve to prevent recurrence.
Side Effects
The most common side effects of Vibramycin include nausea, vomiting, diarrhea, loss of appetite, mild stomach cramps, and sunburn after exposure to UV light. To reduce gastric distress, it is recommended to take the tablets with food or milk.
More serious side effects that may need medical attention include severe diarrhea, fever, sore throat, severe nausea, and extreme fatigue. Allergic reactions like skin rash, itching, swelling, and difficulty breathing can occur in those hypersensitive to tetracyclines. It can also increase blood pressure in some individuals.
Interactions and Warnings
It is important to consult a doctor before using Vibramycin if you have liver or kidney disease, are on antacids, or take blood thinners. Doxycycline may interfere with the contraceptive pill and make it less effective. It also makes skin more prone to sunburn so adequate sun protection is necessary. The tablets should not be taken by pregnant or breastfeeding women as they may impact bone and teeth development in infants.
Price in Pakistan
Vibramycin is available at all major pharmacies across Pakistan. Vibramycin 100mg tablets are priced between PKR 90-150 per 10 tablets strip depending on the pharmacy and brand. The total cost for a standard 100-tablet course of Vibramycin 100mg is approximately PKR 900-1500. The injection formulations are more expensive than tablets. Generic doxycycline hyclate options may be cheaper than the branded Vibramycin.
Conclusion
In conclusion, Vibramycin is an effective broad-spectrum antibiotic used for a variety of bacterial infections. It stops bacteria from multiplying by inhibiting protein synthesis. The standard dosage is 100-200mg per day for 7-14 days. Side effects are usually mild but certain precautions should be taken. The average cost of Vibramycin 100mg tablets in Pakistan is around PKR 90 per 10 tablets. When used responsibly under medical guidance, it is a safe and reliable antibiotic.
FAQs
Q1. What is Vibramycin used for?
A1. Vibramycin is an antibiotic used to treat many common bacterial infections like respiratory infections, urinary tract infections, acne, chlamydia, gonorrhea, and certain eye infections. It can also prevent and treat malaria.
Q2. How does Vibramycin work?
A2. Vibramycin works by stopping bacteria from making proteins that are needed for growth. This prevents them from multiplying and spreading infection.
Q3. What are the side effects of Vibramycin?
A3. Common side effects include nausea, diarrhea, stomach pain, loss of appetite, and increased sunburn sensitivity. More severe side effects are rare but may include severe diarrhea, allergic reactions, and high blood pressure.
Q4. What is the correct dosage of Vibramycin for adults?
A4. The standard adult dosage is 100-200 mg taken once or twice daily. The total daily dose can range from 100-600 mg depending on the type of infection being treated.
Q5. How should Vibramycin be taken?
A5. Vibramycin tablets should be taken whole with a full glass of water. They can be taken with or without food. Try to take doses at the same time each day. Complete the full course as prescribed.
Q6. How long does it take for Vibramycin to work?
A6. Vibramycin starts working within 24 hours, but it may take a few days to see significant improvement in symptoms. Keep taking it even after you start feeling better.
Q7. Can Vibramycin be taken with other medications?
A7. It can interact with certain antibiotics, blood thinners, and antacids. Tell your doctor about all medicines you take before starting Vibramycin.
Q8. Is Vibramycin safe for pregnant or nursing women?
A8. No, Vibramycin should be avoided in pregnancy and breastfeeding as it may impact bone/teeth development in the baby.
Q9. How much does Vibramycin cost in Pakistan?
A9. The price of Vibramycin 100mg tablets in Pakistan is approximately PKR 90-150 for 10 tablets. A 100-tablet course costs around PKR 900-1500.
Q10. What precautions should I take with Vibramycin?
A10. Avoid direct sunlight as it can cause sunburns. Use sunscreen and protective clothing if going out. Call your doctor if you experience severe diarrhea, nausea, or allergic reaction.
